Premature ovarian failure - Rejuvenate Health

Premature Ovarian Failure (POF)

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is when a woman's ovaries stop functioning normally before age 40. The ovaries produce fewer hormones and eggs than usual, which can cause infertility, early menopause, and other health issues.

Some key points about POF:

• Causes: Genetics, autoimmune disorders, chemotherapy/radiation therapy, chromosomal abnormalities, infections, etc. The cause is often unknown.
• Symptoms: Irregular periods, hot flashes, vaginal dryness, night sweats, mood changes, loss of bone density, etc. Symptoms are similar to natural menopause but occur much earlier.
• Diagnosis: Blood tests to measure hormone levels (FSH, estradiol, etc). Also may involve genetic testing, ultrasound or biopsy of the ovaries.
• Risk factors: Family history, autoimmune diseases, cancer treatment at a young age, smoking, etc. POF is rare before age 30.
• Treatment: Hormone therapy with estrogen/progestin to relieve symptoms. Oocyte or embryo freezing may be done after diagnosis to preserve fertility. No way to restart ovarian function.
• Impact: Inability to have biological children, psychological effects, higher risk for other health conditions. Support groups and counseling may help cope.

What should women with POF know?

• Seek help for symptoms right away, don't assume it's normal to have very early menopause. The earlier POF is diagnosed, the more options are available.
• Ask about egg/embryo freezing if hoping to get pregnant in the future. Success rates vary.
• Hormone therapy is crucial to prevent complications like osteoporosis and heart disease. Find an endocrinologist experienced in treating POF patients at a reputable clinic like Rejuvenate Health.
• Connect with support groups to get advice and cope with the emotions of early loss of fertility. You are not alone.

While having POF can be devastating for young women planning families, early diagnosis, hormone therapy, and emotional support allow one to live healthy and full lives. Advancements in fertility preservation and treatments provide hope as well. Remember - POF patients can still achieve motherhood through alternatives like egg donation, embryo adoption, or surrogacy.

Stay positive!